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Ghent’s New High-Throughput Experimentation Centre for Innovative Pharmaceutical Research

Ghent’s New High-Throughput Experimentation Centre for Innovative Pharmaceutical Research

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Published on 12 June 2024

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Ghent University, in collaboration with Johnson & Johnson and the City of Ghent, has launched Belgium's first academic high-throughput experimentation laboratory, the 'HighTru Lab'. Professor Christian Stevens explained that the laboratory is: "A crucial step in the development of new chemical methodologies, new medicines, and the training of tomorrow's engineers and biomedical professionals".

High-Throughput Experimentation (HTE) is a method where a large number of experiments are conducted simultaneously using automated equipment and robotics. This technology is now also being applied in chemical and pharmaceutical research to quickly collect and analyse large amounts of data. HTE processes vast volumes of data using sophisticated data management systems, and miniaturization techniques which save on materials and space. The pharmaceutical industry already uses this approach to quickly screen compounds for biological activity. Thanks to automation and the rapid processing of experiments, HTE is highly cost-effective, and accelerates innovation.

Ghent’s new laboratory is temporarily housed in the CAPTURE building on the Eiland Zwijnaarde business park.  At the end of 2026, it will move to the nearby Nucleus building, which is currently under construction. The Nucleus building will also house CESPE (the Centre of Excellence in Sustainable Pharmaceutical Engineering and Manufacturing).

Multidisciplinary Engagement and Educational Impact

The HighTru Lab illustrates the multidisciplinary approach of Ghent University, with four faculties — Bioscience Engineering, Pharmaceutical Sciences, Engineering and Architecture, and Sciences — all working together. This initiative will benefit not only the academic community, but also the chemical and pharmaceutical sectors by providing training opportunities through an open access lab, contributing to the economic strengthening of Europe.

“With the establishment of the HighTru Lab, we strengthen our position as an innovation leader in the region and the sector,” said Professor Christian Stevens (Research Group “Synthesis, Bioresources and Bioorganic Chemistry”, Ghent University). “This lab will be crucial in the development of innovative chemical methods and new medicines, and offers us the opportunity to train our students to become the engineers and biomedical professionals of tomorrow.”

Collaboration and Societal Impact

This project was reinforced by an educational grant from Johnson & Johnson, making the HighTru Lab a unique knowledge centre in Flanders.

It has also received significant funding through the European Union’s Resilience Fund, and additional funding from the Spearhead Fund of the City of Ghent. Ghent’s Alderman for Economy, Sofie Bracke, said: “With the Spearhead Fund, we as a government invest in large, ambitious projects in the technology sector. These investments are crucial for the further economic development of Ghent, and demonstrate our commitment to supporting high-tech innovations,”

The City of Ghent acknowledges the significance of Ghent as a leading biotechnology and medical hub in Europe and actively supports this project as part of their commitment to sustainability and the health sector.

You can find more information about the HighTru Lab here: HighTru High-Throughput Experimentation Centre Ghent

 

About the partners:

Ghent University is a leading educational and research institution in Belgium, known for its innovative approaches in science and technology.

The City of Ghent is dedicated to promoting local and regional economic development through education and innovation.

Johnson & Johnson is a global leader in healthcare, focusing on the development of pharmaceuticals and improving access to effective medicines.